HLA Class I Allele Frequencies in Southern Iranian Women with Breast Cancer
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HLA Class I Allele Frequencies in Southern Iranian Women with Breast Cancer
OBJECTIVE(S) Breast cancer is the leading cause of cancer-related death in women worldwide. It has been revealed that elevated risk for malignancy may be associated with certain HLA alleles. This study was performed to assess the association of HLA class I alleles with breast cancer in women in Southern Iran. MATERIALS AND METHOD Eighty nine patients included for analyzing the HLA class I all...
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introduction: human leukocyte antigen (hla) genes are the most polymorphic loci in the human genome. they predict the outcome of transplantation by detecting self from non-self antigens. the best use of hla typing is to find a hla-match donor for bmt candidate patients. evidence suggests that matching unrelated donors and recipients for hla-a, -b and -drb1 loci is a prediction for an improved o...
متن کاملleukocyte antigen (hla) class ii allele frequencies in female patients with breast cancer: a case control study
background: the study aimed to examine the association between human leukocyte antigen (hla) class ii allele frequencies and breast cancer in iranian women. methods: a total of 100 patients with pathologically proven breast cancer who referred to cancer institute were randomly selected and compared with a group of age matched healthy blood donors (n = 80). hla class ii alleles were determined b...
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Previous studies demonstrated significant differences in a number of HLA allele frequencies in leukemia patients and normal subjects. In this study, we have analyzed HLA class II alleles and haplotypes in 110 leukemia patients (60 acute myelogenous leukemia "AML", 50 chronic myelogenous leukemia"CML") and 180 unrelated normal subjects. Blood samples were collected from all of the patients and c...
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عنوان ژورنال
دوره 16 شماره 2
صفحات 140- 143
تاریخ انتشار 2013-02-01
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